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1

TEMPORARY REMOVAL: Point of Departure (PoD) Selection for the Derivation of Acceptable Daily Exposures (ADEs) for Active Pharmaceutical Ingredients (APIs)

Bercu, Joel P., Morinello, Eric, Sehner, Claudia, Shipp, Bryan K., Weideman, Patricia A.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.14 MB

english, 2016

2

TEMPORARY REMOVAL: Using Default Methodologies to Derive an Acceptable Daily Exposure (ADE)

Faria, Ellen C., Bercu, Joel P., Dolan, David G., Morinello, Eric J., Pecquet, Alison M., Seaman, Christopher, Sehner, Claudia, Weideman, Patricia A.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2016

Language:

english

File:

PDF, 570 KB

english, 2016

3

Carcinogenicity assessment of the Hedgehog pathway inhibitor, vismodegib in Tg.rasH2 mice and Sprague-Dawley rats

Li, Jinze, Morinello, Eric, Larsen, Thomas, Frost, Denzil, Caro, Ivor, Gould, Stephen, Wong, Lisa, Hendricks, Angela, Dybdal, Noel, Dambach, Donna, Schutten, Melissa

Journal:

Regulatory Toxicology and Pharmacology

Year:

2017

Language:

english

File:

PDF, 891 KB

english, 2017

4

Sinken des Augeninnendrucks und der okularen Pulsamplitude während der Intubationsnarkose

Zuche, H., Morinello, E., Viestenz, A., Fiorentzis, M., Seitz, B., Volk, T., Viestenz, A.

Journal:

Der Ophthalmologe

Year:

2015

Language:

german

File:

PDF, 579 KB

german, 2015

5

Dose, tissue and species transitions in biomarkers

James Swenberg, Gunnar Boysen, Nadia Georgieva, Eric Morinello, Patricia Upton, Vernon Walker

Journal:

Year:

2006

Language:

english

File:

PDF, 71 KB

english, 2006

6

Muscle Relaxants as a Risk Factor for Vis-à-tergo During Penetrating Keratoplasty: A Prospective Interventional Study

Fiorentzis, Miltiadis, Morinello, Emanuela, Viestenz, Anja, Zuche, Hanna, Seitz, Berthold, Viestenz, Arne

Journal:

Advances in Therapy

Year:

2017

Language:

english

File:

PDF, 692 KB

english, 2017

7

Linking Pharmacokinetics and Biomarker Data to Mechanism of Action in Risk Assessment

Swenberg, James A., Gorgeiva, Nadia, Ham, Amy, Koc, Hasan, Morinello, Eric, Ranasinghe, Asoka, Upton, Patricia, Walker, Vernon

Journal:

Human and Ecological Risk Assessment An International Journal

Year:

2002

Language:

english

File:

PDF, 502 KB

english, 2002

8

PONV nach Strabismus-OP

Wolf, R., Morinello, E., Kestler, G., Käsmann-Kellner, B., Bischoff, M., Hager, T., Schöpe, J., Eberhart, L. H. J.

Journal:

Der Anaesthesist

Year:

2016

Language:

german

File:

PDF, 360 KB

german, 2016

9

Embryo-fetal development study of the hedgehog pathway inhibitor vismodegib

Morinello, Eric, Pignatello, Michael, Goelzer, Petra, Villabruna, Loris, Bürgin, Heinrich

Journal:

Reproductive Toxicology

Year:

2013

Language:

english

File:

PDF, 53 KB

english, 2013

10

Absence of toxic effects in F344/N rats and B6C3F1 mice following subchronic administration of chromium picolinate monohydrate

M.C. Rhodes, C.D. Hébert, R.A. Herbert, E.J. Morinello, J.H. Roycroft, G.S. Travlos, K.M. Abdo

Journal:

Food and Chemical Toxicology

Year:

2005

Language:

english

File:

PDF, 334 KB

english, 2005

11

Embryofetal Development Study of Vismodegib, a Hedgehog Pathway Inhibitor, in Rats

Morinello, Eric, Pignatello, Michael, Villabruna, Loris, Goelzer, Petra, Bürgin, Heinrich

Journal:

Birth Defects Research Part B: Developmental and Reproductive Toxicology

Year:

2014

Language:

english

File:

PDF, 225 KB

english, 2014

12

Oral Bioavailability of Polychlorinated Dibenzo-p-Dioxins/Dibenzofurans in Industrial Soils

Finley, Brent, Fehling, Kurt, Warmerdam, John, Morinello, Eric

Journal:

Human and Ecological Risk Assessment An International Journal

Year:

2009

Language:

english

File:

PDF, 381 KB

english, 2009

13

The use of non-tumor data in cancer risk assessment: reflections on butadiene, vinyl chloride, and benzene

Richard Albertini, Harvey Clewell, Matthew W Himmelstein, Eric Morinello, Stephen Olin, Julian Preston, Louis Scarano, Martyn T Smith, James Swenberg, Raymond Tice, Curtis Travis

Journal:

Regulatory Toxicology and Pharmacology

Year:

2003

Language:

english

File:

PDF, 355 KB

english, 2003

14

Immunoaffinity/Gas Chromatography/High-Resolution Mass Spectrometry Method for the Detection of N 2 ,3-Ethenoguanine

Ham, Amy-Joan L., Ranasinghe, Asoka, Morinello, Eric J., Nakamura, Jun, Upton, Patricia B., Johnson, Francis, Swenberg, James A.

Journal:

Chemical Research in Toxicology

Year:

1999

Language:

english

File:

PDF, 233 KB

english, 1999

15

High Risk Individual Counseling by Registered Dietitians As a Risk Based Form of Nutrition Education/Intervention to Participants of the Special Supplemental Nutriton Program for Women, Infants and Children

M.T. Zaczkowski, H. Cattlett, V.J. Morinello, C. Wachtler, K. Eugenio, D. Irwin, Edna Cannata

Journal:

Journal of the American Dietetic Association

Year:

1999

File:

PDF, 136 KB

1999

16

Simultaneous Quantitation of N 2 ,3-Ethenoguanine and 1, N 2 -Ethenoguanine with an Immunoaffinity/Gas Chromatography/High-Resolution Mass Spectrometry Assay

Morinello, Eric J., Ham, Amy-Joan L., Ranasinghe, Asoka, Sangaiah, Ramiah, Swenberg, James A.

Journal:

Chemical Research in Toxicology

Year:

2001

Language:

english

File:

PDF, 116 KB

english, 2001

17

DNA adducts: effects of low exposure to ethylene oxide, vinyl chloride and butadiene

James A Swenberg, Amy Ham, Hasan Koc, Eric Morinello, Asoka Ranasinghe, Natalia Tretyakova, Patricia B Upton, Kuen-Yuh Wu

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2000

Language:

english

File:

PDF, 211 KB

english, 2000

18

Interplay of Dissolution, Solubility, and Nonsink Permeation Determines the Oral Absorption of the Hedgehog Pathway Inhibitor GDC-0449 in Dogs: An Investigation Using Preclinical Studies and Physiologically Based Pharmacokinetic Modeling

Wong, H., Theil, F.-P., Cui, Y., Marsters, J. C., Khojasteh, S. C., Vernillet, L., La, H., Song, X., Wang, H., Morinello, E. J., Deng, Y., Hop, C. E. C. A.

Journal:

Drug Metabolism and Disposition

Year:

2010

Language:

english

File:

PDF, 2.28 MB

english, 2010

19

The postoperative analgesic effect of local applicated S(+)-ketamine after inguinal hernia surgery: A double-blinded, randomized, controlled trial

Knoll, H., Oehrlein, R., Pradarutti, S., Morinello, E., Schreiber, J.

Journal:

European Journal of Anaesthesiology

Year:

2008

Language:

english

File:

PDF, 98 KB

english, 2008

20

Beeinflussung der okulären Pulsamplitude und des Intraokulardrucks durch nicht depolarisierende Muskelrelaxanzien

Zuche, H., Morinello, E., Viestenz, Anja, Fiorentzis, M., Volk, T., Seitz, B., Viestenz, Arne

Journal:

Klinische Monatsblätter für Augenheilkunde

Year:

2015

File:

PDF, 188 KB

2015

21

Impact of different intraoperative CO2 pressure levels (8 and 15 mmHg) during laparoscopic hysterectomy performed due to benign uterine pathologies on postoperative pain and arterial pCO2 : a prospective randomised controlled clinical trial

Radosa, Julia C, Radosa, Marc P, Schweitzer, Pascal A, Radosa, Christoph G, Stotz, Lisa, Hamza, Amr, Takacs, Zoltan, Lepper, Philipp M, Wagenpfeil, Stefan, Linxweiler, Maximilian, Morinello, Emanuela,

Journal:

BJOG: An International Journal of Obstetrics and Gynaecology

Year:

2019

Language:

english

File:

PDF, 209 KB

english, 2019

22

Erratum: Beeinflussung der okulÃ¤ren Pulsamplitude und des Intraokulardrucks durch nicht depolarisierende Muskelrelaxanzien

Zuche, H., Morinello, E., Viestenz, Anja, Fiorentzis, M. F., Volk, T., Seitz, B., Viestenz, Arne

Journal:

Klinische Monatsblätter für Augenheilkunde

Year:

2015

File:

PDF, 23 KB

2015

23

Determination of GDC-0980 (apitolisib), a small molecule dual phosphatidylinositide 3-kinase/mammalian target of rapamycin inhibitor in dog plasma by LC-MS/MS to support a GLP toxicology study

Ding, Xiao, Salphati, Laurent, Kim, Amy, Morinello, Eric, Wong, Lisa, Pang, Jodie, Percey, Shaundel, Meng, Min, Reuschel, Scott, Dean, Brian

Journal:

Biomedical Chromatography

Year:

2015

Language:

english

File:

PDF, 541 KB

english, 2015

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